Immune defence
Natural killer cells are your first line of defence. Losing four hours of sleep cut their activity to 72% of normal.
Irwin et al., Psychosomatic Medicine, 1994
A guided, technical program of specific frequencies to lower your anxiety at night.
$1 a nightMP3, no app45-day refund

68%of US adults say anxiety keeps them up at night. AASM survey, 2024 · 2,006 adults
Natural killer cells are your first line of defence. Losing four hours of sleep cut their activity to 72% of normal.
Irwin et al., Psychosomatic Medicine, 1994In deep sleep, the brain clears out waste about twice as fast as when awake.
Xie et al., Science, 2013 · study in miceAfter four short nights, fat cells responded 30% less to insulin, the hormone that turns food into energy.
Broussard et al., Annals of Internal Medicine, 2012A week of sleeping under six hours changed how 711 genes behave, including genes for immunity and repair.
Möller-Levet et al., PNAS, 2013After a night without sleep, the brain's alarm centre reacted 60% more strongly to upsetting images. Everything starts to feel like a threat.
Yoo et al., Current Biology, 2007Results from published sleep studies, not from the Calma Lab program. The 21 nights help you fall asleep faster and sleep through the night.
The voice slows your breathing from about 14 to 6 breaths a minute, the pace linked to a calmer nervous system.
21 sessions like this, ready offline tonight.
Instant download · one paymentTap the circle to listen. Headphones, low volume. On iPhone, turn off silent mode.
Liked it? The program has 21 of these, ready offline.
Start the 21 nights · $21528 Hz
Next step: no checking the time tonight
It's only a download. Listen in airplane mode, and nothing interrupts your sleep.
A free tool to reset whenever you need it during your day. It's box breathing, the calm-down technique the US military teaches, guided over a 528 Hz tone.
One email with the download. No spam, unsubscribe anytime.
For relaxation and general wellbeing. Not medical advice. If you've felt like this for weeks, please talk to a professional.
21 guided audios of 15–17 minutes (MP3), one for each night, plus a workbook and 21-night tracker (PDF). The frequencies are 528, 432, 396, 417 and 174 Hz, paced to about six breaths a minute. You get the download link right after checkout and by email. The guiding voice is an AI narrator we designed to sound slow and calm at night.
Slow, steady sound gives your mind something calm to follow and slows your breathing, which helps calm the nervous system. That often eases anxiety at night. We don't promise a cure; we give you a routine to repeat. The evidence for specific frequencies like 528 Hz is early; the evidence for slow breathing and calming music is stronger.
No app. Open the download link on your phone: on iPhone the files save to the Files app, on Android to Downloads. Then switch to airplane mode and press play. Works on any phone or computer, with no account, no ads and no notifications.
That's what the 21-Night Promise is for. Try it for up to 45 days. If it doesn't help you relax, email hello@calmalaboratory.com and we'll refund you in full. No forms.
We only quote what each study actually found, and we tell you how strong the evidence is. Every source is linked.
Listening to music may improve sleep quality in adults with insomnia symptoms.
Moderate evidenceRead the reviewFive minutes a day of breathwork improved mood over a month, and anxiety fell in every group. Cyclic sighing helped most.
One trialRead the summaryBreathing at 5.5 to 6 breaths a minute raised heart rate variability, a sign of a calmer nervous system, compared with normal breathing.
One lab studyRead the abstractIn a small pilot, piano music tuned to 528 Hz lowered stress markers more than the same music at 440 Hz.
Early evidenceRead the paperNone of these studies tested Calma Lab itself. They're why we built it the way we did: slow pace, steady tone, guided breath.
